Ay highway speed felt vigorous vibration throughout out my 2001 gmc hd 2500 4x4 as i slowed down it got worse next thing i heard was a loud crunch and banging and a puff of smoke, the truck fish tailed side to side (due to the tire still being inflated,it did not lose air pressure) and i corrected it to safely stop . what had happened was i lost the tread off the rear drivers side tire, causing severe damage to the wheel well and fender and exhaust. *tr